About PK-Swift
Who built it, why it exists, and what it stands for.
Who Built PK-Swift
Jay is a licensed pharmacist and senior researcher at a pharmaceutical company, specializing in drug development and pharmacokinetic analysis. He has multiple years of experience in non-compartmental analysis (NCA), bioequivalence (BE) studies, and PK/PD modeling.
In his professional work, Jay routinely uses commercial PK software such as Phoenix WinNonlin (retail price: $30,000+/year) for regulatory-grade pharmacokinetic analysis. He knows these tools inside and out — their strengths, their limitations, and the science behind them.
Outside of pharmaceutical research, Jay is an indie developer under Vibed Lab, building tools that make scientific analysis more accessible.
Why PK-Swift Was Built
Commercial pharmacokinetic software is extraordinarily expensive. A single license for industry-standard tools like Phoenix WinNonlin can cost $30,000 or more per year — pricing that puts professional-grade PK analysis out of reach for:
- Graduate students learning pharmacokinetics for the first time
- Academic researchers without institutional software licenses
- Pharmacists and clinicians who need quick PK estimates
- Scientists in developing countries where expensive software is inaccessible
- Independent researchers who cannot justify the license cost for exploratory work
Jay built PK-Swift to change that. As someone who works with these calculations every day professionally, he implemented the same underlying mathematics — derived from publicly available textbook knowledge — in a free, browser-based platform that requires no installation and no license fee.
The goal: give students, researchers, and clinicians a reliable, transparent, and free tool for pharmacokinetic analysis.
Scientific Rigor & Validation
PK-Swift is not a casual project. Its algorithms are implemented from first principles based on established pharmacokinetic textbooks and peer-reviewed literature:
- Gabrielsson & Weiner — Pharmacokinetic & Pharmacodynamic Data Analysis, 5th ed. (2016)
- Rowland & Tozer — Clinical Pharmacokinetics and Pharmacodynamics, 4th ed. (2010)
- Gibaldi & Perrier — Pharmacokinetics, 2nd ed. (1982)
- Wagner — Fundamentals of Clinical Pharmacokinetics (1975)
PK-Swift includes an automated validation benchmark that compares computed NCA parameters against the Theophylline Subject 1 reference dataset — an FDA-referenced standard dataset commonly used to validate PK software.
All computations run entirely in your browser. Your patient data, research data, and PK values never leave your machine (except when you explicitly use the optional AI Parse feature).
What PK-Swift Is — and Isn't
PK-Swift is designed for:
- Education: Teaching and learning NCA, BE, IVIVC, and PK concepts
- Research: Exploratory analysis, rapid hypothesis testing, data visualization
- Cross-validation: Verifying computations against other software
- Publication-quality graphs: Journal-ready concentration-time visualizations
PK-Swift is NOT validated under 21 CFR Part 11 or any regulatory framework. It should not be used as the sole basis for regulatory submissions to the FDA, EMA, or other agencies. For regulated work, use commercially validated software. See our full Disclaimer & Legal Notice.
Part of Vibed Lab
PK-Swift is part of Vibed Lab — a collection of free, browser-based tools built by Jay for science, finance, and productivity. All Vibed Lab tools share the same philosophy: professional-grade functionality, completely free, with zero installation required.
Other tools in the Vibed Lab ecosystem:
- VORA — AI meeting assistant with real-time speech recognition (vora.vibed-lab.com)
- CryptoBacktest — Bitcoin trading strategy backtesting platform (bt.vibed-lab.com)
Contact
Questions, feedback, or collaboration inquiries? Reach out:
- Email: contact@vibed-lab.com
- Website: https://vibed-lab.com